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Studies show that the majority of adults do not adhere to a prescribed pharmacologic regimen. Some of them take less than the prescribed dose while others will take more, which can lead to either underdose or accidental overdose. Some don't bother to fill new prescriptions or discontinue the medication altogether without discussing with their physician.
http://ezinearticles.com/?A-Pill-Dispenser-Could-Reduce-Medication-Non-Adherence&id=9556318